Description

Myeloma specifically involves abnormal plasma cells that accumulate in the bone marrow and interfere with the production of normal blood cells. Here are some key points about myeloma: 1. Abnormal plasma cells: In myeloma, plasma cells become cancerous and multiply uncontrollably, crowding out healthy blood cells in the bone marrow. The abnormal plasma cells produce an excess amount of monoclonal antibodies, which are abnormal proteins that can impair organ function. 2. Bone involvement: Myeloma commonly affects the bones, leading to bone pain, fractures, and skeletal abnormalities. The excessive activity of the abnormal plasma cells can cause damage to the bone structure and lead to weakened bones. 3. Symptoms: The symptoms of myeloma can vary but may include bone pain, fatigue, weakness, recurrent infections, unexplained weight loss, frequent thirst and urination, and anemia (low red blood cell count). 4. Diagnosis: Myeloma is diagnosed through a combination of blood tests, bone marrow biopsy, and imaging studies, such as X-rays, CT scans, or MRI scans. Blood tests can detect abnormal protein levels, such as monoclonal antibodies or free light chains, and other markers indicative of myeloma. 5. Staging: Myeloma is staged based on several factors, including the presence or absence of certain symptoms, blood test results, and imaging findings. The staging system helps determine the extent and severity of the disease and guides treatment decisions. 6. Treatment: Treatment for myeloma depends on various factors, including the stage of the disease, the overall health of the patient, and individual preferences. Common treatment approaches include chemotherapy, targeted therapy, immunotherapy, stem cell transplantation, radiation therapy, and supportive care to manage symptoms and complications. 7. Prognosis: The prognosis for myeloma varies widely and depends on several factors, including the stage of the disease, the patient's age and overall health treatment.

Filter tags